Healthcare & Wellness Businesses for Sale in Chicago, IL

This luxury medical aesthetics and nail lounge business operates from a fully leased multi-tenant retail strip center in the Chicago suburbs, with the commercial real estate included in the asking price. The business has built strong name recognition in its market through high-end aesthetic, wellness, and beauty services offered in a professionally designed facility. Owning the underlying real estate alongside the operating business creates a dual-return structure with both operating cash flow and commercial property income.

This medical aesthetics and wellness practice in the Chicago metro area offers a broad range of services including injectables, laser treatments, PRP restoration, advanced facials, medical weight loss, and IV therapy, with a medical director in place and a loyal expanding client base. The business has operated for over a decade, generating strong recurring revenue through scheduled appointments and customized treatment plans. The diversified service menu and established patient relationships provide a stable platform for continued growth or additional service expansion.

This licensed home health agency in the Chicago metro area serves a multi-county Illinois territory and maintains a census of approximately 70 patients under Medicare and managed care plans. The business has demonstrated revenue stability with consecutive years of growth approaching $850,000 in annual revenue and is 36-month-rule exempt, providing compliance certainty that is highly valuable to acquirers in the home health sector. Healthcare-specific industry experience is required, making this best suited for an existing home health operator or licensed clinical buyer.

Three physical therapy franchise locations operating in a high-demand Chicago suburban corridor benefit from strong brand recognition, proven clinical systems, and comprehensive franchisor support that allows non-clinical ownership. The suburban market has demonstrated robust and growing demand for outpatient therapy services, and the franchise model reduces operational risk relative to an independent clinic. A new owner does not need a clinical background, making this accessible to business operators with general management experience.

A multi-provider orthopedic practice in the Chicago suburbs with over three decades of operating history, a 9,000 square foot facility, and a referral-dominant patient acquisition model. The practice treats a broad range of musculoskeletal conditions and has maintained consistent profitability from a stable provider team and loyal patient base. Seller willingness to remain through transition reduces continuity risk for a new physician owner or practice management group.

This non-medical home care agency in northwest Indiana has operated since 2018, serving seniors and adults with disabilities through attendant care, homemaking, companionship, transportation, and chore services for both Medicaid-funded and private-pay clients. The business generated over $1.3 million in SDE in its strongest recent year, reflecting strong regional demand for in-home support services in an aging population. The seller is open to seller financing with a qualified buyer, reducing the capital barrier to entry for an owner-operator seeking a foothold in the essential services sector.

This Chicago-area mental health practice has grown consistently since founding, reaching over $845,000 in 2025 revenue with strong profit margins and an established patient base supported by a comprehensive insurance panel including Medicare and Medicaid. High employee retention and a committed clinical team reduce transition risk and support continuity of care for existing patients. The practice's demonstrated growth trajectory and broad payer mix position it well for continued expansion under new ownership.

This pediatric therapy practice delivers occupational, physical, and speech therapy services through in-home and community-based care models in the greater Chicago metro area. The business has established referral networks with healthcare partners and serves a growing population of pediatric clients through evidence-based, individualized treatment protocols. Recurring referral-driven demand and the essential nature of developmental pediatric services provide stable, predictable revenue for a new owner.

This membership-based primary care practice in the Chicago metro area operates on an all-cash model outside traditional insurance constraints, delivering predictable recurring revenue from a loyal patient panel. The practice was built over more than two decades by an experienced physician, resulting in a well-earned reputation for personalized, accessible care. The model is well-suited for a physician seeking clinical autonomy or a healthcare group looking to expand with a proven, capital-efficient template.